Obesity Study Self-Scheduler

Basic Criteria: 

• Must be 18 years or older.

• Must have a BMI greater than or equal to 30 OR 27 with a weight‑related condition [calculate here].

• Must be taking weekly semaglutide (≥0.5 mg) or tirzepatide (≥5 mg) and have been on the same dose for at least 90 days.

• Must be willing to self‑inject weekly and use study diaries.

Answers Must Be No: 

• Have you had weight‑loss surgery or endoscopic/device weight procedures?

• Have you used insulin, amylin drugs, DPP‑4 inhibitors, other GLP‑1s, GIP/GLP‑1s, or weight‑loss medications in the last 90 days?

• Do you have Type 1 Diabetes or a history of diabetic ketoacidosis?

• Do you have severe hypoglycemia episodes or unawareness?

• Do you have uncontrolled high glucose (fasting >270 mg/dL)?

• Do you have significant heart, kidney, liver, autoimmune, endocrine, or psychiatric conditions as described in exclusion criteria?

• Have you had pancreatitis?

• Are you pregnant, breastfeeding, or planning pregnancy?

• Have you recently taken medications that cause major weight gain (unless on stable dosing for >6 months)?

• Are you currently in another clinical trial?

• Do you have recent suicidal ideation or high PHQ‑9 score (≥15)?

• Did you lose more than 3% of body weight during the 8‑week lead‑in?

Answers Must Be Yes 

• Are you 18 years or older?

• Are you currently taking weekly semaglutide (0.5 mg+) or tirzepatide (5 mg+) and have been on the same dose for at least 90 days?

• Is your BMI greater than or equal to 30 OR 27 with a weight‑related condition (hypertension, dyslipidemia, OSA, CVD, or T2D)?

• Has your weight been stable (within 5%) for the last 90 days?

• Are you willing to continue your current incretin therapy?

• If you can become pregnant or are AMAB, are you willing to follow study birth‑control requirements?

• Are you available for all visits over about 12 months?

• Are you able to give informed consent and follow study visits?

• Are you willing to self‑inject weekly and use study diaries?

PLEASE NOTE: Please confirm your eligibility before your appointment by calling 312-931-8883

• If you do not see an available appointment, please call 312-931-8883 for availability.

• Transportation may be available. Call 312-931-8883 

• Compensation may be available for time and travel.

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