Flourish Research

Cardiovascular – Lp(a) Self-Scheduler

To qualify for this study, participants must: 

  • Be ages 18 or older AND one of the following applies to you:
    • Coronary artery disease
    • Stroke or carotid stenting
    • Peripheral arterial disease, lower extremity (PAD)


  • Be 55 or older with one or more:
    • Coronary Artery Disease
    • Peripheral arterial disease (PAD)
    • Known familial hypercholesterolemia (either by diagnosis or LDL ≥ 100 mg/dL while on lipid-lowering medication


  • Are you 55 years or older with three or more of the following:
    • 65 or older for Males
    • 70 or older for Females
    • Current tobacco use
    • High blood pressure
    • Kidney disease
    • Diabetes
    • Family history of premature cardiovascular events (heart attack or coronary bypass surgery in father or brother younger than 55; heart attack or coronary bypass surgery in mother or sister younger than 60)
    • Coronary Artery Calcium (CAC) score
      •  ≥300 for anyone
      • ≥100 for individuals assigned female at birth < 65 years of age
    •  High cholesterol
      • LDL-cholesterol ≥ 100 mg/dL (2.59 mmol/L), on maximally tolerated lipid-lowering therapy


  • Not have had a heart attack, stroke, or coronary or peripheral revascularization in the past 3 months
  • Not have received a coronary artery score of 0 in the past 5 years
  • Not have had cancer in the past 5 years ( except skin, cervix, or prostate cancer)
  • Not have any active infection or major diseases
  • Not be pregnant or breastfeeding
  • Not have taken any of the following medications for lowering Lp(a):
    • Lepodisiran
    • Muvalaplin
    • Pelacarsen
    • Olpasiran
    • Zerlasiran
    • Obicetrapib
  • Be on stable lipid-lowering medications in the past month, if on lipid-lowering medication
  • Be on a stable PCSK inhibitor in the past 2 months, if on a PCSK inhibitor
  • Be willing to take a highly effective form of birth control
  • Additional criteria will apply  


PLEASE NOTE: Please confirm your eligibility before your appointment by calling +1 210-949-0122 

If you do not see an available appointment, please call +1 210-949-0122 for availability. 

Transportation may be available. Call +1 210-949-0122Compensation up to $1,680 is available for time and travel.

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